Tehran threatens retaliation after reported strikes and assassinations, while Israel urges residents to seek shelter and the UK reaffirms support for its ally’s right to defend itself.

Scientists have unveiled a new blood test for Alzheimer’s that shows promising accuracy for early detection, potentially enabling thousands to receive earlier intervention and reassurance if they do not have the disease.

Amid mounting tension over planned cuts to disability benefits, senior party figures warn they will step down from the frontbench unless the leader shifts position, with proposals to delay the changes until 2027 also under discussion.

Reform UK has surged to a 10-point lead over Labour, intensifying debate over the viability of the two-party system and fuelling speculation about a potential shift in the political landscape.