The PM conceded Peter Mandelson’s vetting was mishandled, saying officials failed to pass on key information. Conservatives accused him of blame‑shifting, increasing pressure on his leadership and prompting scrutiny of No 10’s appointments process.

Labour MPs urge the PM to accept responsibility for errors surrounding Peter Mandelson’s appointment as ambassador to Washington, after reports he was approved despite failing security vetting. With local elections looming, pressure mounts and some call for his resignation.

Calls for Keir Starmer to quit after claims he misled MPs about Peter Mandelson’s security clearance ahead of his appointment as US ambassador. Critics say checks were failed; the PM maintains due process was followed. Pressure for clarification in Parliament is mounting.

A Cochrane review says Alzheimer’s drugs targeting amyloid offer only a trivial gain in cognition and daily living over 18 months. Charities reject the verdict, arguing lecanemab and donanemab represent genuine progress for patients and research.